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Category: BRCA Journal Club

Home Archive by Category "BRCA Journal Club"

Inherited Mutations in Women With Ovarian Carcinoma.

7th March 2016Daniel ReiselBRCA Journal Club

Germline mutations in BRCA1 and BRCA2 are relatively common in women with ovarian, fallopian tube, and peritoneal carcinoma (OC) causing a greatly increased lifetime risk of these cancers, but the frequency and relevance of inherited mutations in other genes is less well characterized. This study set out to determine the frequency and importance of germline…

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Precision Medicine Meets Public Health: Population Screening for BRCA1 and BRCA2

7th March 2016Daniel ReiselBRCA Journal Club

Mutations in BRCA1 and BRCA2 were first discovered in the mid-1990s in families with multiple cases of breast and ovarian cancer and remain the major cause of inherited susceptibility to these malignancies. At first, testing for mutations in these genes was limited to women with cancer diagnosis at a young age or with a substantial…

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BRCA Mutation Testing Increasing in Younger Women

19th February 2016Daniel ReiselBRCA Journal Club

The proportion of women diagnosed with breast cancer at 40 years of age or younger who undergo BRCA1 and BRCA2 mutation testing is increasing, according to a new study. In fact, the proportion went from 77% in 2006 to 95% in 2013, Shoshana M. Rosenberg, ScD, MPH, from the Dana-Farber Cancer Institute in Boston, and…

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Recent Posts

  • Inherited Mutations in Women With Ovarian Carcinoma.
  • Precision Medicine Meets Public Health: Population Screening for BRCA1 and BRCA2
  • Skin sparing mastectomy
  • What to ask your consultant
  • Advice for those considering breast surgery

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Latest Posts

  • Inherited Mutations in Women With Ovarian Carcinoma. 7th March 2016
  • Precision Medicine Meets Public Health: Population Screening for BRCA1 and BRCA2 7th March 2016
  • Skin sparing mastectomy 19th February 2016

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